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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASGRP1 All Species: 14.55
Human Site: S33 Identified Species: 35.56
UniProt: O95267 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95267 NP_001122074.1 797 90402 S33 L E A K P A N S P F P S H P S
Chimpanzee Pan troglodytes XP_001165459 689 78238
Rhesus Macaque Macaca mulatta XP_001092164 797 90549 S33 L E A K P A N S P F P S H P S
Dog Lupus familis XP_535429 624 71069
Cat Felis silvestris
Mouse Mus musculus Q9Z1S3 795 90285 S33 L E A K S T N S P L P A Q P S
Rat Rattus norvegicus Q9R1K8 795 90226 S33 L E A K S T N S P L P A Q P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511025 724 82163 T10 G V H S I S L T L Y F L H Y T
Chicken Gallus gallus XP_001233089 744 85631 S30 S F D L E G N S Y Q N N Q L L
Frog Xenopus laevis Q6NTL4 791 90153 T33 K Q I I H S T T H P K V P A V
Zebra Danio Brachydanio rerio NP_001103934 708 80321
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.9 98.3 74.9 N.A. 90.3 89.8 N.A. 48.6 70.7 71 47.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 63.8 99 76.6 N.A. 93.2 93.2 N.A. 64.1 81 81.8 62.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 0 N.A. 66.6 66.6 N.A. 6.6 13.3 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 100 0 N.A. 73.3 73.3 N.A. 33.3 20 20 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 40 0 0 20 0 0 0 0 0 20 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 40 0 0 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 20 10 0 0 0 0 % F
% Gly: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 10 0 10 0 0 0 10 0 0 0 30 0 0 % H
% Ile: 0 0 10 10 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 40 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 40 0 0 10 0 0 10 0 10 20 0 10 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 50 0 0 0 10 10 0 0 0 % N
% Pro: 0 0 0 0 20 0 0 0 40 10 40 0 10 40 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 10 0 0 30 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 10 20 20 0 50 0 0 0 20 0 0 40 % S
% Thr: 0 0 0 0 0 20 10 20 0 0 0 0 0 0 10 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _